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NeuroPharmacoGenetics Lab

About

Our laboratory is interested in the genetic basis of complex brain disorders, including genetic predisposition for alcoholism, drug use, and other compulsive behaviors, as well as molecular mechanisms underlying such neuro-sensory processes as neuropathic pain, analgesia, and diabetic neuropathy.

Research Aim(s)

  • Genetic predisposition to alcoholism, drug abuse, and other compulsive behaviors in human
  • Genetic factors influencing alcohol drinking in rodent models
  • Behavioral patterns of alcohol preference and social environment in rodent models
  • Molecular mechanisms of neuro-sensory processes, including pain, stress, and analgesia

Active Research Projects

  • Rodent models of alcohol drinking, and influence by social environment and gender
  • Human genetic variations that impact alcohol drinking, drug use, and other compulsive behaviors
  • Brain-expressed genes associated with alcohol preference and relapse
  • Physiological analysis of spinal cord neuro-sensory systems in nerve pain
  • Rodent models of analgesia with genetic and pharmacological therapeutics
  • Cell and rodent models to identify protein networks underlying nerve pain and alcoholism
  • Rodent models to identify potential drugs for treating nerve pain and alcoholism
  • Computational analysis of genetic impact in longitudinal alcoholism studies
  • Genetic and computational analysis of diabetic neuropathy and inflammation-mediated chronic pain


Personnel

Core Faculty:
Lei Yu, PhD
Arthur Tomie, PhD
Students:
Aayushi Parikh
Akash Patel
Akhila Manthena
Aleeza Usman
Allyson Graves
Aman Mathew
Amay Mehta
Amogh Kudva
Ananya Mahalingam
Angelica Petersen
Anika Patel
Anisha Singhal
Anitej Thamma
Annie Lin
Anveshi Prakash
Asha Mathew
Deblina Mukherjee
Demi Poulathas
Doria Elhalafawy
Drew Johnson
Esha Paghdal
Fiza Iftikhar
Haider Salam
Jillian Rivera
Justine Soltys
Kate Liu
Kathryn Chan
Kishan Patel
Krishna Goli
Lauren Craft
Manal Hajjam
Mary Kopchick
Nafee Ullah
Peter Ni
Ria Medasani
Ruksar Rahman
Saloni Jain
Sarah Mostafa
Shaili Soni

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